[BDC] Uptake cholesterol enter cells by receptor-mediated endocytosis

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Brazilian Journal of Education of Biochemistry and Molecular Biology

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Uptake cholesterol enter cells by receptor-mediated endocytosis

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Note	(4 votes) Evaluate
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Discipline	Biochemistry
Publication in	12/04/2007, 13:54
Sent by	Elaine Aparecida de Oliveira

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Summary

LDL is a low-density lipoprotein, very rich in cholesterol and cholesteryl esters, contending one specific apoprotein. The bilding of apoprotein to an LDL receptors initiates process of endocytosis, which conveys the LDL and its receptor into the cell within an endosome. The endosome fuses with a lysosome, which contains enzymes that hydrolyze the cholesteryl esters, releasing cholesterol and fatty acid into the cytosol, and the LDL receptor returned to the cell surface, to function again in LDL uptake.

General Information
Authors	Elaine Aparecida De Oliveira
Keywords	LDL, cholesterol, cholesteryl esters, receptor-mediated endocytosis.

Citation (ABNT)

OLIVEIRA, E. A. Uptake cholesterol enter cells by receptor-mediated endocytosis Biblioteca Digital de Ciências, 12 apr. 2007. Available in: <http://www.ib.unicamp.br/lte/bdc/visualizarMaterial.php?idMaterial=465>. Access in: 25 may. 2013.

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