As disciplinas de Bioquímica básica, normalmente, utilizam aulas expositivas ou a dinâmica de estudo em grupo como estratégias de ensino teórico. A revisão dos conceitos abordados em sala de aula é realizada, frequentemente, através de exercícios clássicos de fixação. Por outro lado, nos últimos anos, os livros texto têm sido acompanhados de CDs, que contem várias de suas figuras animadas e vinculadas a hipertextos e a links de páginas da internet, que facilitam a construção de significados do conhecimento bioquímico. Paralelamente, objetos de aprendizagem em ambientes virtuais têm sido desenvolvidos com conteúdos informativos, podendo estar associados ou não a propostas desafiadoras, estimulando o aluno a desempenhar um papel mais ativo no entendimento dos conceitos bioquímicos básicos. É neste contexto que se insere este trabalho, constituindo-se num objeto de aprendizagem mediado por computador, no qual se apresenta, interativamente, a “Síntese de Glicogênio Hepático pelas Vias Direta e Indireta”. A sua concepção e criação foram realizadas através da plataforma Adobe e seu conteúdo bioquímico foi baseado em informações divulgadas em artigos científicos e em livros texto. Com isto, pretende-se disponibilizar mais um objeto de aprendizagem ao repositório de SOFTWAREs educacionais, para auxiliar no estudo de Bioquímica, tratando de um tema ainda não contemplado por esta estratégia de ensino.

 (7 votos)

Categoria: Artigo Científico

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Autores: Vera Maria Treis Trindade, Bruno Pastoriza, Luciene Pinheiro Vianna, Christianne Gazzana Salbego, José Del Pino

Palavras-chave: Objeto de aprendizagem, glicogênese hepática, via direta, via indireta.

The benefits of using INTERACTIVE computer SOFTWAREs in Education have been discussed for some time. This approach can improve cognitive capacity, better learning and, mainly, it makes information acquisition easier. This work presents the development of a SOFTWARE called SISFISIO. It is an “exercise and practice” system designed for teaching Physiology in biomedical courses. It was developed using the Delphi interface system and Macromedia Flash. The Flash components were integrated with Delphi using an ActiveX control. The internal structure of the SOFTWARE has two linearly-linked lists (a linked list is one of the fundamental data structures used in computer programming): one for the exercises and another for the question of each exercise. The information is stored in a text file that should be filled by the instructor. The SISFISIO SOFTWARE uploads this file and it fills the data structures cited above. Upon completion of a Physiology module, the student’s answers can be immediately verified, the scores tallied and the duration of the exercise measured.SISFISIO was incorporated into biomedicine classes at USS. The student’s evaluation, based on the 5-point Likert questionnaire and spontaneous comments, has indicated that the SOFTWARE has facilitated the learning of physiological concepts and was a very stimulating activity.

Categoria: Resumo da SBBq

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Autores: Tallita Vassequi Silva, Alves, R.s.p., Avelar, J.l.v., Guiné, A.a.a., Pêgo, P.n., Carvalho, C. V. A., De Mesquita, J.f.

Palavras-chave: Education, Physiology, SOFTWARE

Computers became a common learning tool since basic education until the post-graduation. Professors have used presentations, sites and other multimedia resources to modify and improve classes. Biochemistry presents a large amount of dynamic processes and the learning journey is benefited by elaborated drawings and colored animations as well. Some interaction with the biochemical processes assists pupils to perceive the functioning of varied cycles and its relations. Student participation in the pedagogical process, such as social constructionism and distance learning are also realities in Biochemistry learning. The present work proposes the establishment of a free SOFTWARE based classroom system. The employment of a CD-started system brings freedom, independent of the operating system currently installed and not modifying it. The system adopted was GNU/Linux. With its tools, it was possible to create a full system with all the required programs for simulated lessons, INTERACTIVE navigation, illustrations and presentations, included as Biochemistry didactic material. Even old computers can be used. The implementation of remote terminal system enables very slow equipments to become useful accessing a process share with another better equipment. Free SOFTWARE packages were included to allow students to open and edit text, presentations, worksheets, images and PDF documents. A program was especially developed aiming at the professor control over the various computers improving the interaction among the classroom within the computational environment. The above described system was inserted in a single CD. It can be used within MS-Windows, Mac-OS or GNU/Linux operating systems, as a source of Biochemistry didactic material, or be executed as a “boot disk” to replace any operating system. This technique is called LIVE-CD, where the system is loaded directly of a removable media. The original operational system installed will not be affected until requested by the user. Also the already existing archives can be accessed by the system. The server terminal possibility is in agreement with the system concept: the freedom of its implementation with any kind of computer, since very limited hardware can still be used as terminals. As perspectives for the near future, the live-CD system will be able to run services such as web, database and PHP, enabling even more student participation in the learning process.

Categoria: Resumo da SBBq

Idiomas disponíveis:

Autores: R. S. Rodrigues, Wagner Fontes, M. S. Castro

Palavras-chave: Development, terminals system, Biochemist, education

This work describes some of the possible cognitive operations related to the use of an educational game type activity, which is part of the SOFTWARE e-metabolismo, developed to improve biochemical learning. This INTERACTIVE activity, called DMDV – Dynamic Metabolic Diagram, allows participants to drag-and-drop components of the sequence of chemical reactions, which describe the metabolic route under study. It also offers to the students quizzes and texts about the subject. The suggestion of cognitive processes possibly triggered by the SOFTWARE, which must improve effective learning, was based on Jean Piaget’s genetic epistemological ideas to explain the cognitive activity. One of these processes is the mere act of playing the game, which Piaget relates to humans needs of learning rules of socialization. It also can be seen as a first step in cognition process, the so called adaptation function that include assimilation and accommodation, INTERACTIVE processes between intelligent activities and elements from the reality, to became part of the individual´s mental structures. Another example: drag and drop substracts and enzymes pieces in a virtual board, each one corresponding to an specific place in a metabolic route. This operation can be related to motivation, an affective element proposed by Piaget to stimulate curiosity and improve construction of knowledge structures. Besides this issue, the act of choosing pieces is assumed to inform the student previous knowledge (previous cognitive structures), which, according to Piaget, must be misbalanced (equilibration of new structures is supposed to be part of the dynamic process of organization of new knowledge). DMDV was tested with a group of 24 students (2003) and another group of 36 students in 2004, of a Biochemistry Course regularly registered at FFFMCPA´s medicine faculty. The evaluation of the student’s apprenticeship was made by a conventional test and three Conceptual Maps constructed by each student, (a) before playing the game, (b) immediately after, and (c) three months after the use of the game.

 (1 votos)

Categoria: Resumo da SBBq

Idiomas disponíveis:

Autores: A. M. P. Azevedo, L.c. Fagundes, M. L. Zaro, M. I. Timm

Palavras-chave: Cognitive Processes, Digital Game, Dinamic Metabolic Diagram Virtual Krebs Cycle

Biological membranes define cellular boundaries, divide cells into discrete compartments, organize complex reaction sequences, and act in signal reception and energy transformations. This topic is studied in all undergraduate biochemistry courses. Visualization of structures generally facilitates the understanding of many related topics of membrane composition, structures, and protein interactions but they lack in many events that occurs in membranes. Also, at the present time, animations exploring solubilization and reconstitution of membrane proteins in vesicular systems are not available. Thus, we have developed a SOFTWARE named AnimaBio, in Macromedia Flash 7.0, whose principal objective was the animation of some processes used in the study of membrane biology and it was didactically divided in: (1) composition and physics properties; (2) construction of systems mimetically to natural membranes and (3) characterization of these biomimetic systems using experimental examples. The topics explained in each section were: (1) Membranes composition; lipids and proteins distribution; fluid mosaic model; the basic structural unit of lipid bilayer; peripheral proteins; anchored proteins; integral proteins; covalently attached oligosaccharides; solubilization of proteins and hemolytic effects; (2) construction of biomimetical systems using different techniques; sonication followed by direct insertion of proteins and co-solubilization methods; (3) Kinetic properties of the enzyme, reconstituted in the vesicular system, using examples of actions of different agents such as: inhibitors, detergents, ionophores and photosensitive dyes. All topics were illustrated in the animation using some examples such as: erythrocytes membranes; alkaline phosphatase (which have a GPI anchor) and integral proteins such as Na,K-ATPase. AnimaBio has many animations exploring some fragile concepts and each part was also explained in a text. Some items were enriched with glossary definitions, compound structures and technical terminology. This approach allows the student to have a non-fragmented view of membrane biology and to understand the importance of a given interaction of lipid and protein as a whole. Thus, the SOFTWARE provides a non-passive study facilitating the comprehension of this important topic in the biochemistry course and also motivating the student to search the literature for similar examples. Supported by: FAPESP, CNPq and CAPES

 (1 votos)

Categoria: Resumo da SBBq

Idiomas disponíveis:

Autores: Ivana Aparecida Borin, Eneida De Paula, Pietro Ciancaglini

Palavras-chave: INTERACTIVE SOFTWARE, study, membrane biology